Nobel prize winners research led to Velcade

Avram Hershko and Aaron Ciechanover were the first Israelis to receive the Nobel in the sciences. They received the prize for their discovery of the ubiquitin system of regulated protein degradation, a fundamental process that influences vital cellular events and has been implicated in cancer and many other diseases, including Alzheimer's. This discovery led to the development of Velcade, a drug used to treat multiple myeloma.